Penelitian ini bertujuan untuk menganalisis pengaruh pengangguran dan pertumbuhan ekonomi terhadap kualitas Sumber Daya Manusia (SDM) di Provinsi Kalimantan Utara, khususnya pada aspek pendidikan (diukur dari indeks gabungan Rata-rata Lama Sekolah/RLS dan Harapan Lama Sekolah/HLS) dan kesehatan (diwakili Angka Harapan Hidup/AHH). Metode penelitian menggunakan pendekatan deskriptif kuantitatif dengan analisis regresi linier berganda, data sekunder diperoleh dari Badan Pusat Statistik (BPS) Provinsi Kalimantan Utara periode 2014–2024, serta melalui Uji asumsi klasik dipenuhi sebelum analisis. Hasil penelitian menunjukkan bahwa: (1) Secara parsial, pengangguran berpengaruh negatif dan signifikan terhadap kualitas SDM baik pada aspek pendidikan maupun kesehatan; (2) Sebaliknya, pertumbuhan ekonomi tidak berpengaruh signifikan pada kedua aspek; (3) Secara simultan, pengangguran dan pertumbuhan ekonomi berpengaruh signifikan terhadap kualitas pendidikan dan kesehatan, dengan pengangguran sebagai variabel dominan. Implikasi penelitian menyoroti pentingnya: (1) Reformasi kebijakan ketenagakerjaan untuk mengurangi pengangguran terdidik; (2) Optimalisasi alokasi anggaran pendidikan dan kesehatan sesuai standar internasional; (3) Pemerataan layanan dasar guna memutus hubungan negatif pengangguran-SDM. Pertumbuhan ekonomi berbasis sumber daya alam terbukti gagal meningkatkan kualitas SDM tanpa kebijakan inklusif. Kata Kunci: Pengangguran, Pertumbuhan Ekonomi, Pendidikan, Kesehatan, Kualitas SDM

The Influence of Unemployment and Economic Growth on Human Resource Quality in North Kalimantan Province. This Study aims to analyze the influence of unemployment and economic growth on the quality Human Resources (HR) in North Kalimantan Province, explicitly focusing on education (measured by combined index of Average Years of Schooling/RLS and Expected Years of Schooling/HLS) and health (represented by Life Expectancy/AHH). The study method employs a quantitative decriptive approach with multiple linear regression analysis. Secondary data wereobtained from the Central Statistics Agency (BPS) of North Kalimantan Province for 2014-2024. Classical assumption tests were performed before the analysis. The resultsindicate that: (1) Partially, unemployment has a negative and significant influence on HR quality in both the education and health aspects; (2) Conversely, economic growth does not have a siginificant influence on either aspects; (3) Simultaneously, unemployment and economic growth significantly influence the quality of education and health, with unemployment being the dominant variable. The implications of the study highlight the importance of (1) Reforming labor policies to reduce educated unemployment, (2) Optimizing the allocation of education and health budgets by international standards, and (3) Ensuring equitable distribution of basic services to break the negative relationship between unemployment and HR quality. Resource-based economic growth was ineffective in improving HR quality without inclusive policies. Keywords: Unemployment, Economic Growth, Education, Health, HR Quality