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One Of The Types Of Mental Disorders Are The Most Functional Psychosis Is Schizophrenia. Epidemiological Study Mentions That Estimates Of The Prevalence Of Schizophrenia In General Ranged From 0.2% To 0.15%. Social Isolation Is A Disorder That Occurs Due To The Presence Of Interpersonal Personality Inflexible Cause Maldaptif Behavior And Disrupt The Function Of A Person In A Social Relationship. Based On Medical Record Data In Tarakan District General Hospitals In 2013 The Number Of Mental Patients As Many As 251 People With A Number Of Social Isolation Of Patients Were 42 Deaths From January To September. 2014 Data On The Number Of Mental Patients As Many As 153 People With The Number Of Patients Of Social Isolation Is As Much As 49 People From January To July. Of The Incidence Of Social Isolation On The Number Of Patients From 2013 To 2014 Has Increased, For The Authors Are Interested In Doing Nursing Care To Mr. B With The Main Issues Of Social Isolation: Withdrawal In The General Hospital Area Tarakan Comprehensively Through The Mental Approach To The Nursing Process Assessment, Determination Of Nursing Diagnoses, Nursing Action Plan, And Implement Nursing Actions And Evaluation Of Such Action. In The Preparation Of This Final Report Writer Uses Descriptive Method In The Form Of A Case Study Approach To The Nursing Process. Assessment Of The Results Found In The Case Of Mr. 3 Diagnoses. B, Namely: Social Isolation: Withdrawal, Impaired Self-Concept: Low Self Esteem, And Self-Care Deficit: Bathing And Ornate. Of The Three Diagnoses That All Issue Can Be Resolved In Accordance With The Objectives And Time Specified. Keywords: Schizophrenia, Social Isolation