Penelitian bertujuan untuk menghasilkan petunjuk praktikum berbasis inkuiri terbimbing pada materi pencemaran lingkungan yang sesuai dengan karakteristik anak sma dan menghasilkan produk petunjuk praktikum berbasis inkuiri terbimbing pada materi pencemaran lingkungan yang berkualitas dari aspek kelayakan, kepraktisan, dan keefektifan. penelitian ini merupakan penelitian dan pengembangan (research and development) dari model borg & gall yang dimodifikasi oleh sugiyono (2015) yang dibatasi sampai pada tahap ke sembilan. instrumen penelitian dan pengembangan ini menggunakan lembar pedoman wawancara guru, pedoman wawancara siswa, angket validasi ahli materi, angket validasi ahli desain, angket respon guru, angket respon siswa, dan lembar observasi keterpakaian produk. uji coba produk menggunakan siswa kelas x sebanyak 6 orang dan uji coba lapangan utama menggunakan siswa kelas x sebanyak 30 orang. petunjuk praktikum memiliki tiga karakteristik yaitu: petunjuk praktikum berbasis inkuiri terbimbing, struktur petunjuk praktikum, dan materi petunjuk praktikum. kualitas petunjuk praktikum diperoleh dari aspek kelayakan, kepraktisan dan keefektifan. pada aspek kelayakan dari hasil validasi ahli materi sebesar 96% dengan kategori sangat layak, ahli desain sebesar 77% dengan kategori layak. pada aspek kepraktisan, angket respon guru biologi sebesar 88% dengan kategori sangat praktis, hasil angket kepraktisan respon siswa uji coba produk sebesar 89% dengan kategori sangat praktis, angket kepraktisan respon siswa uji coba pemakaian sebesar 83% dengan sangat praktis, observasi keterpakaian petunjuk praktikum sebesar 94% dengan sangat praktis. pada aspek keefektifan, hasil angket keefektifan respon siswa uji coba produk sebesar 90% dengan kategori sangat efektif, dan angket keefektifan respon siswa uji coba pemakaian sebesar 83% dengan sangat efektif. berdasarkan dari hasil tersebut dapat disimpulkan petunjuk praktikum yang dikembangkan berkualitas.

The aims of the study were to develop a guided inquiry lab instruction on environmental pollution topic based on for high school students characteristicss and to know the quality a product of guided inquiry lab instruction on environmental pollution topic which was related to its validity, pratical, effectivity. this study was research and development of borg & gall model which was modified by sugiyono (2015) and limited to the ninth step. instruments that were used in this study were interview sheet for the teacher, interview sheet for student, questionaire of topic validation, questionaire of design validation, questionaire of teacher’s respond, questionaire of students’ respond, and observation sheet of product practical. the products were applied to 6 students of tenth graders for trial and the field test was conducted by 30 students. a guided inquiry lab instruction has three characteristics: developed based on guided inquiry model, the structure and material of lab instruction. the quality of product was based on the validity, practicality and effectivity. for validity aspect, it was obtained from the result of topic and design validator which was 96% which showing that it was very valid, for design validator got 77% showing that it was valid. for practial aspect, the questionaire responses for teacher was 88% showing that the product was very practical, the result of questionaire from studentts responses on trial was 89% which mean very practical, the results of questionaire from students’ responses on field study was 83% which mean very practical, and the results of observation sheet for product practicality were 94% which mean very practical. for effectivity aspect, the result of students’ responses were 90% which mean very effective, students’ responses in field study were 83% which mean very effective. it could be concluded that the lab instruction that was qualified.