Herniated nucleus pulposus atau yang sering disebut dengan sakit punggung bagian bawah (low back pain) merupakan salah satu penyakit tidak menular yang umum dijumpai pada seluruh masyarakat, baik secara global maupun nasional. sekitar 90% hnp terjadi di area lumbosacral spine, 8% di area cervical spine dan 1% hingga 2% di area thoracic spine. apabila seseorang terdiagnosis hnp maka perlu dilakukan perawatan secara profesional dengan durasi waktu yang cukup lama dan biaya yang mahal disertai resiko kejadian berulang. hal ini tentu akan berpengaruh pada seluruh aspek kehidupan diantaranya kondisi ekonomi, keharmonisan keluarga, kualitas kehidupan dan kejiwaan seseorang. penelitian ini betujuan untuk mengetahui hubungan tingkat depresi dengan kualitas hidup pasien herniated nucleus pulposus di rsud dr. h. jusuf sk tarakan provinsi kalimantan utara. jenis penelitian ini adalah kuantitatif dengan desain penelitian studi penampang analitis (analytic cross-sectional study). populasi pada penelitian ini adalah pasien dengan diagnosa medis herniated nucleus pulposus dengan pengambilan sampel menggunakan purposive sampling sebanyak 51 responden. penelitian ini menggunakan uji statistik uji spearman rank. hasil uji statistik menunjukkan bahwa nilai signifikansi 0,000 < 0,05 dengan coefficient correlation -0,75 sehingga menunjukkan ada hubungan yang signifikan antara tingkat depresi dengan kualitas hidup dengan kekuatan hubungan kuat dan arah hubungan negatif. kesimpulan penelitian ini ialah semakin tinggi tingkat depresi maka semakin rendah kualitas hidup pasien herniated nucleus pulposus atau semakin rendah tingkat depresi maka semakin tinggi kualitas hidup pasien. kata kunci: depresi, kualitas hidup, herniated nucleus pulposus

Herniated nucleus pulposus or what is often referred to as lower back pain is a non-communicable disease that is common in all societies, both globally and nationally. the humbosacral spine accounts for about 90% of hnp, the cervical spine for 8%, and the thoracic spine for 1% to 2%. when someone is diagnosed with hnp, they must undergo professional therapy, which is expensive, time- consuming, and accompanied by reoccurring episodes. all facets of life, including the economy, family peace, quality of life, and psychological health, will undoubtedly be impacted by this. the purpose of this study was to ascertain how the quality of life of patients with herniated nucleus pulposus at dr. h. jusuf sk tarakan, north kalimantan province, correlated with their level of depression. this kind of study had a quantitative cross-sectional study design with analytical components. having a purposive sampling size of 51 participants, the population in this study consisted of patients with a herniated nucleus pulposus diagnosis. the spearman rank test was a statistical test used in this investigation. the results of the statistical test indicated that there was a significant relationship between the degree of depression and quality of life, with the strength of a strong relationship and the direction of a negative relationship, with a significance value of 0.000 0.05 and a correlation coefficient of -0.75. according to this study's findings, people with herniated nucleus pulposus had lower quality of life when their depression levels were higher or higher quality of life when their depression levels were lower. keywords: depression, quality of life, hnp